FRESENIUS DIASAFE PLUS DIALYSIS FLUID FILTER
The Fresenius Diasafe Plus Dialysis Fluid Filter is a key step towards good dialysis practice that produces ultrapure dialysis fluid and provides sterile & non-pyrogenic substitution fluid.
KEY FEATURES
- Dialysis Fluid Purity: In order to avoid endotoxin related complications during routine hemodialysis, the usage of ultrapure water is strongly recommend. Ultrapure water or dialysis fluid can easily be achieved through the application of special dialysis fluid filters such as Diasafe Plus
- Chronic Inflammation: The usage of ultrapure dialysis fluid has been shown to reduce markers of chronic inflammation in hemodialysis patients, therefore it is suggestive that ultrapure dialysis fluid has a beneficial effect on inflammatory diseases such as atherosclerotic CVD
- Oxidative Stress: This type of stress is associated with the progression of malnutrition, anemia and inflammatory diseases such as atherosclerosis, the usage of ultrapure dialysis fluid to reduce dialysis induced oxidative mechanisms appears desirable
- Advanced Glycation End Products (AGE): The importance of ultrapure dialysis fluid in routine hemodialysis treatments is emphasized by the finding that endotoxins act in synergy with advanced glycation end products (AGE), which enhance inflammation and oxidative stress10. The use of ultrapure dialysis fluid has further been shown to reduce the plasma levels of the AGE compound pentosidine
- Anemia Treatment: Ultrapure dialysis fluid has been shown to improve iron utilization and the response to erythropoietin, meaning it could be beneficial in anemia treatment by allowing for a reduced erythropoietin dosage while maintaining optimal hemoglobin levels
TECHNOLOGY
Located at the end of the water treatment chain, the Diasafe Plus filter ensures required purity levels can be achieved easily through the reliable production of ultrapure dialysis fluid to ISO Standards. The Diasafe Plus incorporates the Fresenius Polysulfone membrane which has excellent endotoxin retention capabilities due to the superior adsorptive and sieving characteristics of the membrane. The extended surface area of 2.2m² further extends the adsorption and retention capacity.
- Hygienic, Fast, Easy Installation & Exchange
The Diafix lock system provides an easy and hygienic connection of the Diasafe Plus to the dialysis machine with only three handling steps necessary for installation or exchange:
1. Open the locks of the filter holder
2. Slide Diasafe Plus filter into the guide grooves
3. Close the locks - Diasafe Plus is ready to use. It’s that easy!
- ONLINE Plus System
1. The ultrapure dialysis fluid prepared with Diasafe Plus together with hemodialyzers containing endotoxin retaining membranes are the main building blocks for a high quality hemodialysis treatment
2. The Online Plus system takes the quality standards of convective treatment modalities such as hemodiafiltration / hemofiltration (HDF/HF) one step further
for reliable production of sterile and non-pyrogenic substitution fluid by double filtration
3. Improving hygiene and safety of convective therapy modalities, the Online Plus option also offers additional treatment features and easier handling
SPECIFICATIONS
- Membrane Material: Fresenius Polysulfone
- Effective Surface: 2.2 m²
- Weight: 170 gms
- Housing Material: Polypropylene
- Potting Material: Polyurethane
- Sealings: Silicone
- Connection to Machine: DIAFIX Lock System
- Filtration Rate: 5 ml/min x mm Hg (3.75 L/min bar; max. 2 bar)
- Operating Time:
Standard HD - Max. 12 weeks or 100 treatments ONLINE HF/HDF
ONLINE Priming/Rinsingax - Max12 weeks or 100 treatments
- Disinfection:
Puristeril 340 or Puristeril Plus (Peracetic Acid)
Diasteril (Hydroxyacetic Acid) or Citrosteril (Citric Acid)
Sporotal 100 (Sodium Hypochlorite) - Max. 11 times